The fine line between autoimmune and allergic encephalomyelitis
Howard L. Weiner
Harvard Medical School, Center for Neurologic Diseases, Brigham and Women's Hospital, 77 Ave Louis Pasteur, HIM 720 Boston, MA 02115, USA. weiner@cnd.bwh.harvard.edu
What determines whether immune responses against a self-peptide can evoke an anaphylactic response? New evidence describes anaphylaxis that appears to be governed by thymic expression of the self-antigen.