Per Brandtzaeg, Espen S. Baekkevold
& H. Craig Morton
Laboratory for Immunohistochemistry and Immunopathology (LIIPAT), Institute of Pathology, University of Oslo, Rikshospitalet, N-0027 Oslo, Norway. per.brandtzaeg@labmed.uio.no
Generation of intestinal secretory IgA depends on antigen induction of B cells in organized GALT. A recent paper in Nature reports that in mice the lamina propria provides signals that direct mucosal B cells to undergo C class switching and as a basis for SIgA production.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated
class switching and as a basis for SIgA production.
R on the lamina propria stromal cells of the gut is required for IgA production
