THEMIS, the enigmatic regulator of T cell selection in the thymus, controls selection by oxidizing and suppressing the activity of the tyrosine phosphatase SHP-1.
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Wiest, D. THEMIS-tery is solved. Nat Immunol 18, 368–370 (2017). https://doi.org/10.1038/ni.3708
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DOI: https://doi.org/10.1038/ni.3708