Throughout ontogeny, the γδ TCR repertoire in human blood becomes less diverse and more focused, yet is private in nature, and specific adult γδ T cell subsets undergo substantial clonal expansion after challenge with cytomegalovirus.
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B.S.-S. is co-founder and shareholder of Lymphact—Lymphocyte Activation Technologies SA.
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Silva-Santos, B., Strid, J. γδ T cells get adaptive. Nat Immunol 18, 370–372 (2017). https://doi.org/10.1038/ni.3705
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DOI: https://doi.org/10.1038/ni.3705
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γδ T cells: origin and fate, subsets, diseases and immunotherapy
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