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Quantifying the shifting landscape of B cell immunodominance

Nature Immunology volume 18, pages 367–368 (2017)Cite this article

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A Corrigendum to this article was published on 18 May 2017

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Antibodies to neutralizing epitopes on hemagglutinin exhibit reproducible dynamic immunodominance patterns over time. Early responses target largely the Cb site, followed by Sb dominance and a concomitant rise in the diversity of neutralizing-antibody specificities.

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Figure 1: Relative immunodominance of five influenza HA head domain sites targeted by neutralizing antibodies changes throughout the course of an immune response to infection of C57BL/6J mice with influenza virus A/PR/8/34.

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  • 03 April 2017

    In the version of this article initially published, a spelling error was made in the citation list. The error has been corrected in the HTML and PDF versions of the article.

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Authors and Affiliations

  1. Jessica R. Shartouny and Joshy Jacob are in the Department of Microbiology and Immunology and the Emory Vaccine Center, Gordon A. Dale, Emory University, Atlanta, Georgia, USA.,

    Gordon A Dale, Jessica R Shartouny & Joshy Jacob

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  1. Gordon A Dale
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  2. Jessica R Shartouny
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  3. Joshy Jacob
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Correspondence to Joshy Jacob.

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Dale, G., Shartouny, J. & Jacob, J. Quantifying the shifting landscape of B cell immunodominance. Nat Immunol 18, 367–368 (2017). https://doi.org/10.1038/ni.3695

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