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Trained macrophages support hygiene hypothesis

Replacement of resident alveolar macrophages by monocyte-derived macrophages after herpesvirus infection protects against asthma.

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Figure 1: Herpesvirus infection induces persisting changes in alveolar macrophages that protect against asthma.

Kim Caesar/Springer Nature

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Correspondence to Michael H Sieweke.

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de Laval, B., Sieweke, M. Trained macrophages support hygiene hypothesis. Nat Immunol 18, 1279–1280 (2017). https://doi.org/10.1038/ni.3874

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