The differentiation of follicular regulatory T cells can be limited by the cytokine IL-2, preventing the emergence of autoantibodies. This research identifies these cells as key regulators of the germinal center response.
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Linterman, M., Toellner, KM. TFR cells trump autoimmune antibody responses to limit sedition. Nat Immunol 18, 1185–1186 (2017). https://doi.org/10.1038/ni.3856
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DOI: https://doi.org/10.1038/ni.3856