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Immunity without innate lymphoid cells

A cohort of immunodeficient children lead near-normal lives after bone marrow transplantation, despite a profound deficiency of innate lymphoid cells (ILCs).

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Figure 1: Immune-cell reconstitution in children with SCID due to mutations in IL2RG or JAK3 after hematopoietic stem cell (HSC) transplantation.

Kim Caesar/ Nature Publishing Group

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Correspondence to Graham Le Gros.

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Weinkove, R., Filbey, K. & Le Gros, G. Immunity without innate lymphoid cells. Nat Immunol 17, 1237–1238 (2016). https://doi.org/10.1038/ni.3567

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