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Maturation of effector regulatory T cells

Nature Immunology volume 12, pages 283–284 (2011)Cite this article

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Regulatory T cells adopt specialized differentiation programs controlled by transcription factors. The transcription factors Blimp-1 and IRF4 are now shown to be pivotal in the maturation of effector regulatory T cells.

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Figure 1: Control of the effector function of Treg cells by transcription factors.

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Authors and Affiliations

  1. Naganari Ohkura and Shimon Sakaguchi are in the Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan,

    Naganari Ohkura & Shimon Sakaguchi

  2. World Premier International Immunology Frontier Research Center, Osaka University, Osaka, Japan

    Naganari Ohkura & Shimon Sakaguchi

Authors
  1. Naganari Ohkura
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  2. Shimon Sakaguchi
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Correspondence to Shimon Sakaguchi.

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The authors declare no competing financial interests.

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Ohkura, N., Sakaguchi, S. Maturation of effector regulatory T cells. Nat Immunol 12, 283–284 (2011). https://doi.org/10.1038/ni0411-283

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