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All GOD's creatures got dedicated mucosal immunity

Nature Immunology volume 11, pages 777–779 (2010)Cite this article

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Mucosal IgA regulates the composition of gut microbiota. IgT in bony fish is now shown to have—via convergent evolution—the same properties as IgA, demonstrating strong evolutionary pressure to preserve both systemic and mucosal immunity.

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Figure 1: Properties of mucosal immunoglobulins among diverse vertebrate taxa.

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Authors and Affiliations

  1. Martin F. Flajnik is in the Department of Microbiology and Immunology, University of Maryland at Baltimore, Baltimore, Maryland, USA.,

    Martin F Flajnik

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  1. Martin F Flajnik
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Correspondence to Martin F Flajnik.

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The author declares no competing financial interests.

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Flajnik, M. All GOD's creatures got dedicated mucosal immunity. Nat Immunol 11, 777–779 (2010). https://doi.org/10.1038/ni0910-777

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