News and Views

Nature Immunology 10, 809 - 811 (2009)
doi:10.1038/ni0809-809

Dead man walking: how thymocytes scan the medulla

Ludger Klein1

  1. Ludger Klein is with the Institute for Immunology, Ludwig-Maximilian-University, Munich, Germany.
    e-mail: ludger.klein@med.lmu.de

The thymic medulla provides a unique milieu for the induction of T cell tolerance. New work now provides a first glimpse of how thymocytes scan this microenvironment and thus maximize their chances of encountering self antigen.

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