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Nature Immunology 10, 806 - 808 (2009)
doi:10.1038/ni0809-806
TH2 bias: Mina tips the balance
Saskia Hemmers1 & Kerri A Mowen1
- Saskia Hemmers and Kerri A. Mowen are in the Department of Chemical Physiology and the Department of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, California, USA.
Correspondence to: Kerri A Mowen1 e-mail: kmowen@scripps.edu
Abstract
Tipping the balance of early cytokine production can lead to lineage bias and, potentially, immune-mediated pathology. Mapping of a leishmania-susceptibility region has identified a gene that may determine the extent of T helper type 2 bias in naive helper T cells.
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RESEARCH
Mina, an Il4 repressor, controls T helper type 2 biasNature Immunology Article (01 Aug 2009)
