News and Views


Nature Immunology 10, 235 - 236 (2009)
doi:10.1038/ni0309-235

Deciding the decider: Mef2c in hematopoiesis

Rachel M Gerstein1

  1. Rachel M. Gerstein is in the Department of Molecular Genetics and Microbiology, Graduate Program in Immunology/Virology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.
    e-mail: rachel.gerstein@umassmed.edu


Factors influencing progenitor cell 'choice' between lymphoid and myeloid lineage fates are incompletely understood. New work implicates the transcription factor Mef2c as one component needed to promote lymphoid and suppress myeloid lineage differentiation.

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