News and Views
Nature Immunology 10, 1047 - 1049 (2009)
doi:10.1038/ni1009-1047
The importance of being earnestly selfish
Hilde Cheroutre1, Daniel Mucida1 & Florence Lambolez1
- Hilde Cheroutre, Daniel Mucida and Florence Lambolez are with the La Jolla Institute for Allergy and Immunology, La Jolla, California, USA.
Correspondence to: Hilde Cheroutre1 e-mail: hilde@liai.org
Abstract
Agonist encounter can divert thymocytes into several unconventional T cell subsets, many of which exhibit regulatory properties. Unexpected findings indicate that agonist selection can drive the differentiation of interleukin 17–producing cells in the thymus.
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