News and Views

Nature Immunology 10, 11 - 12 (2009)
doi:10.1038/ni0109-11

Spotlight on IL-22-producing NK cell receptor–expressing mucosal lymphocytes

Karl-Johan Malmberg1 & Hans-Gustaf Ljunggren1

  1. Karl-Johan Malmberg and Hans-Gustaf Ljunggren are with the Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, S-14186 Stockholm, Sweden.
    e-mail: hans-gustaf.ljunggren@ki.se

New findings show that a subpopulation of mucosal RORgammat+ cells expresses natural killer cell receptors and produces interleukin 22. These innate immune cells may be pivotal in maintaining mucosal homeostasis.

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