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Historical Insight
Nature Immunology  1, 453 - 455 (2000)
doi:10.1038/82691

Clemens Freiherr von Pirquet: Explaining immune complex disease in 1906

Arthur M. Silverstein

Institute of the History of Medicine, Johns Hopkins School of Medicine, 1900 East Monument St., Baltimore, MD 21205, USA.
arts@jhmi.edu

What only one person accomplish in a lifetime? Pirquet, an exceedingly curious pediatrician with acute powers of observation and deduction, not only solved the riddle of serum sickness and developed the concept of allergy, but also made contributions to the study of nutrition and aging.

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Nature Immunology
ISSN: 1529-2908
EISSN: 1529-2916
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