Nature Immunology
1, 367 - 368 (2000)
doi:10.1038/80799
Cytokines, virokines and the evolution of immunitySteven K. Dower
University Division of Genomic Medicine, Royal Hallamshire
Hospital, Sheffield S10 2JF, UK. s.dower@sher.ac.uk
In a new twist, the cytokine IL-10, if present when leukocytes are
activated, can disconnect chemokine receptors from signaling for cell migration.
The receptors act as a "sink" for soaking up chemokines, thus
providing the perfect decoy.
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