Incompatible differences: view of an allogeneic pMHC-TCR complex
David M. Kranz
Department of Biochemistry, University of Illinois
, Urbana, IL 61801, USA.
d-kranz@uiuc.edu
How do T cells recognize allogeneic MHC molecules with such ferocity?
The first crystal structure of an allo-MHC complexed with peptide and T cell
receptor begins to reveal the answer.