Department of Immunology, University of Washington
, Seattle, WA 98195, USA.
pfink@u.washington.edu
Antigen receptor editing is no longer the province of B cells alone.
T cells also can be caught in the act, given the right system. The T cell
receptors of double positive thymocytes that recognize self antigens on the
cortical epithelium with dangerously high affinity will undergo editing until
they get it right.
