Nature Immunology
1, 190 - 192 (2000)
doi:10.1038/79723
Complementing asthmaPeter Henson
National Jewish Medical and Research Center, Department
of Pediatrics, 1400 Jackson St., Rm. D508, Denver
, CO 80206-2761, USA
hensonp@njc.org
The complement inflammatory cascade is crucial to our innate ability
to ward off infection. Two papers now provide evidence linking C5 and C3a
to murine airway hyperresponsiveness, a partial model of human asthma. Surprisingly,
these complement proteins appear to have opposite effects.
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