Intertwining proteins in thymocyte development and cancer
Cornelis Murre
University of California - San Diego, Department of
Biology, La Jolla, CA 92093, USA
. murre@biomail.ucsd.edu
Perturbation of T cell differentiation by overexpression of SCL
and LMO can lead to leukemia. This dysregulation may be initiated by inactivation
of E2A.