Howard Hughes Medical Institute, Rheumatology Division,
Washington University, St. Louis, MO 63110
, USA. yokoyama@imgate.wustl.edu
NK cells become cytotoxic upon receiving a signal through their
activation receptors. The orphan proteins H-60 and Rae1 have now been identified
as ligands for the mouse NKG2D activation receptor. Remarkably they are inducible
and may be blocked by a viral protein.
