Department of Microbiology and Immunology, University of California, San Francisco, CA 94143-0414, USA. (cyster@itsa.ucsf.edu)
Marginal zone B cells may steal the limelight as the roles of Pyk-2 and BLyS begin to be elucidated. Pyk-2 deficiency leads to their loss whereas signaling via the BLyS receptor may augment their function.