Preventing injury from within, using selective cPLA2 inhibitors
Charles N. Serhan
Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. (cnserhan@zeus.bwh.harvard.edu)
The enzyme cPLA2 plays a pivotal role in adult respiratory distress syndrome (ARDS). Specific blocking of cPLA2 may present a useful therapeutic target for treating ARDS.