Focus on Specialized Immunological Niches


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Bone marrow niches

VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

Kaplan, R.N., Riba, R.D., Zacharoulis, S., Bramley, A.H., Vincent, L., Costa, C., MacDonald, D.D., Jin, D.K., Shido, K., Kerns, S.A., Zhu, Z., Hicklin, D., Wu, Y., Port, J.L., Altorki, N., Port, E.R., Ruggero, D., Shmelkov, S.V., Jensen, K.K., Rafii, S. & Lyden, D.

Nature 438, 820-827 (2005).

Abstract | Full text | PDF

Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization

Cancelas, J.A., Lee, A.W., Prabhakar, R., Stringer, K.F., Zheng, Y. & Williams, D.A.

Nat. Med. 11, 886-891 (2005).

Abstract | Full text | PDF

Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis

Avecilla, S.T., Hattori, K., Heissig, B., Tejada, R., Liao, F., Shido, K., Jin, D.K., Dias, S., Zhang, F., Hartman, T.E., Hackett, N.R., Crystal, R.G., Witte, L., Hicklin, D.J., Bohlen, P., Eaton, D., Lyden, D., de Sauvage, F. & Rafii, S.

Nat. Med. 10, 64-71 (2004).

Full text | PDF

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