Selected Classics Chemokines
Examples of Involvement in Disease
Examples of involvement in disease:
Interleukin-8 as a macrophage-derived mediator of angiogenesis.
Koch, A. E., Polverini, P. J., Kunkel, S. L., Harlow, L. A., DiPietro, L. A., Elner, V. M., Elner, S. G. & Strieter, R. M. Science 258 , 1798—801 (1992)
Pubmed
Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8.
Sekido, N., Mukaida, N., Harada, A., Nakanishi, I., Watanabe, Y. & Matsushima, K. Nature 365 , 654—657 (1993)
Pubmed
Inhibition of Interleukin 8 attenuates angiogenesis in bronchogenic carcinoma.
Smith, D. R., Polverini, P. J., Kunkel, S. L., Orringer, M. B., Whyte, R. I., Burdick, M. D., Wilke, C. A. & Strieter, R. M. J. Exp. Med. 179 , 1409—1415 (1994)
Pubmed
Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation.
Jose, P. J., Griffiths-Johnson, D. A., Collins, P. D., Walsh, D. T., Moqbel, R., Totty, N. F., Truong, O., Hsuan, J. J. & Williams, T. J. J. Exp. Med. 179 , 881—886 (1994)
Pubmed
Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice.
Gu, L., Okada, Y., Clinton, S. K., Gerard, C., Sukhova, G. K., Libby, P. & Rollins, B. J. Mol. Cell. 2 , 275—281 (1998)
Pubmed
Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis.
Boring, L., Gosling, J., Cleary, M. & Charo, I. F. Nature 394 , 894—897 (1998)
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Pubmed
Acute and relapsing experimental autoimmune encephalomyelitis are regulated by differential expression of the CC chemokines macrophage inflammatory protein-1alpha and monocyte chemotactic protein-1.
Kennedy, K. J., Strieter, R. M., Kunkel, S. L., Lukacs, N. W. & Karpus, W. J. J. Neuroimmunol. 92 , 98—108 (1998)
Pubmed
