Antigen−specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACspp13 - 21 L.L. Green, M.C. Hardy, C.E. Maynard-Currie, H. Tsuda, D.M. Louie, M.J. Mendez, H. Abderrahim, M. Noguchi, D.H. Smith, Y. Zeng, N.E. David, H. Sasai, D. Garza, D.G. Brenner, J.F. Hales, R.P. McGuinness, D.J. Capon, S. Klapholz
& A. Jakobovits doi:10.1038/ng0594-13 Abstract + references|PDF
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A method for constructing radiation hybrid maps of whole genomespp22 - 28 Michael A. Walter, Dominique J. Spillett, Philip Thomas, Jean Weissenbach
& Peter N. Goodfellow doi:10.1038/ng0594-22 Abstract + references|PDF
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Simple purification of human chromosomes to homogeneity using muntjac hybrid cellspp29 - 33 Jae-Yong Lee, Minoru Koi, Eric J. Stanbridge, Mitsuo Oshimura, Arlene T. Kumamoto
& Andrew P. Feinberg doi:10.1038/ng0594-29 Abstract + references|PDF
(599K)
Male pseudohermaphroditism caused by mutations of testicular 17−hydroxysteroid dehydrogenase 3pp34 - 39 Wayne M. Geissler, Daphne L. Davis, Ling Wu, Karen D. Bradshaw, Sushma Patel, Berenice B. Mendonca, Keith O. Elliston, Jean D. Wilson, David W. Russell
& Stefan Andersson doi:10.1038/ng0594-34 Abstract + references|PDF
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Genomic sequence sampling: a strategy for high resolution sequence−based physical mapping of complex genomespp40 - 47 Michael W. Smith, Anita L. Holmsen, Yalin H. Wei, Melinda Peterson
& Glen A. Evans doi:10.1038/ng0594-40 Abstract + references|PDF
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Striking sequence similarity over almost 100 kilobases of human and mouse T−cell receptor DNApp48 - 53 Ben F. Koop
& Leroy Hood doi:10.1038/ng0594-48 Abstract + references|PDF
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Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strainspp54 - 58 Wade H. Berrettini, Thomas N. Ferraro, Robert C. Alexander, Arthur M. Buchberg
& Wolfgang H. Vogel doi:10.1038/ng0594-54 Abstract + references|PDF
(438K)
Developmental changes in methylation of spermatogenesis−specific genes include reprogramming in the epididymispp59 - 63 Mira Ariel, Howard Cedar
& John McCarrey doi:10.1038/ng0594-59 Abstract + references|PDF
(576K)
Heterozygous missense mutation in the rod cGMP phosphodiesterase −subunit gene in autosomal dominant stationary night blindnesspp64 - 68 Andreas Gal, Ulrike Orth, Wolfgang Baehr, Eberhard Schwinger
& Thomas Rosenberg doi:10.1038/ng0594-64 Abstract + references|PDF
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Mapping a gene for congenital fibrosis of the extraocular muscles to the centromeric region of chromosome 12pp69 - 73 Elizabeth C. Engle, Louis M. Kunkel, Linda A. Specht
& Alan H. Beggs doi:10.1038/ng0594-69 Abstract + references|PDF
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Apolipoprotein E4 allele in a population−based study of early−onset Alzheimer's diseasepp74 - 78 Cornelia M. van Duijn, Peter de Knijff, Marc Cruts, Anita Wehnert, Louis M. Havekes, Albert Hofman
& Christine Van Broeckhoven doi:10.1038/ng0594-74 Abstract + references|PDF
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A null mutation in the human CNTF gene is not causally related to neurological diseasespp79 - 84 Ryosuke Takahashi, Hidehiro Yokoji, Hidemi Misawa, Michiyuki Hayashi, Jianguo Hu
& Takeo Deguchi doi:10.1038/ng0594-79 Abstract + references|PDF
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Mutations of the VHL tumour suppressor gene in renal carcinomapp85 - 90 J.R. Gnarra, K. Tory, Y. Weng, L. Schmidt, M.H. Wei, H. Li, F. Latif, S. Liu, F. Chen, F.-M. Duh, I. Lubensky, D.R. Duan, C. Florence, R. Pozzatti, M. M. Walther, N.H. Bander, H.B. Grossman, H. Brauch, S. Pomer, J.D. Brooks, W.B. Isaacs, M.I. Lerman, B. Zbar
& W.M. Linehan doi:10.1038/ng0594-85 Abstract + references|PDF
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Anaplastic Wilms' tumour, a subtype displaying poor prognosis, harbours p53 gene mutationspp91 - 97 Nabeel Bardeesy, David Falkoff, Mary-Jane Petruzzi, Norma Nowak, Bernhard Zabel, Mohammed Adam, Maria C. Aguiar, Paul Grundy, Tom Shows
& Jerry Pelletier doi:10.1038/ng0594-91 Abstract + references|PDF
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Mutations of the E−cadherin gene in human gynecologic cancerspp98 - 102 John I. Risinger, Andrew Berchuck, Matthew F. Kohler
& Jeff Boyd doi:10.1038/ng0594-98 Abstract + references|PDF
(467K)
Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17qpp103 - 107 Michael R. Stratton, Deborah Ford, Susan Neuhasen, Sheila Seal, Richard Wooster, Lori S. Friedman, Mary-Clarie King, Valgar Egilsson, Peter Devilee, Ross McManus, Peter A. Daly, Elizabeth Smyth, Bruce A.J. Ponder, Julian Peto, Lisa Cannon-Albright, Douglas F. Easton
& David E. Goldgar doi:10.1038/ng0594-103 Abstract + references|PDF
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Bardet−Biedl syndrome is linked to DNA markers on chromosome 11 q and is genetically heterogeneouspp108 - 112 Mark Leppert, Lisa Baird, Kent L. Anderson, Brith Otterud, James R. Lupski
& Richard Alan Lewis doi:10.1038/ng0594-108 Abstract + references|PDF
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4 and early−onset Alzheimer's
−hydroxysteroid dehydrogenase 3
