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A panoramic view of acute myeloid leukemia

A recent study in the New England Journal of Medicine reports the genomic and epigenomic changes in adult acute myeloid leukemia (AML). The patterns of somatic mutation suggest biologically relevant connections between the functional categories of genes driving AML.

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Figure 1: Circos plot showing a panoramic view of genetic events leading to the pathogenesis of AML.

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Correspondence to Zhu Chen.

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Chen, SJ., Shen, Y. & Chen, Z. A panoramic view of acute myeloid leukemia. Nat Genet 45, 586–587 (2013). https://doi.org/10.1038/ng.2651

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