The reprogramming of somatic cells to a pluripotent state is prone to errors that could hamper the use of this technology. A new study now shows that vitamin C enhances the quality of somatic cell reprogramming in mice, highlighting the possibility that further manipulation of culture conditions could improve this technology for regenerative medicine.
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Esteban, M., Pei, D. Vitamin C improves the quality of somatic cell reprogramming. Nat Genet 44, 366–367 (2012). https://doi.org/10.1038/ng.2222
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DOI: https://doi.org/10.1038/ng.2222
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