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The genome of a blood fluke associated with human cancer

Nature Genetics volume 44, pages 116–118 (2012)Cite this article

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The sequencing of the genome and transcriptome of Schistosoma haematobium, a highly prevalent blood fluke and human parasite with a proven link to malignant bladder cancer, marks the 160th anniversary of its discovery as the first schistosome known to infect humans. Comparative genomic analyses of S. haematobium and the more prevalent human-schistosomiasis pathogens (Schistosoma mansoni and Schistosoma japonicum) identified both shared and distinct genomic features.

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Figure 1: An overview of the schistosome life cycle.

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  1. Makedonka Mitreva is at the Genome Institute and Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA.,

    Makedonka Mitreva

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  1. Makedonka Mitreva
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Correspondence to Makedonka Mitreva.

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Mitreva, M. The genome of a blood fluke associated with human cancer. Nat Genet 44, 116–118 (2012). https://doi.org/10.1038/ng.1082

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