A genome-wide association study reports more than a dozen new susceptibility loci for celiac disease. Analysis of eQTL data from these and previously established risk loci sheds light on the genetic pathways underlying this common autoimmune disease.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Dubois, P.C.A. et al. Nat. Genet. 42, 295–302 (2010).
Sollid, L.M. et al. J. Exp. Med. 169, 345–350 (1989).
van Heel, D.A. et al. Nat. Genet. 39, 827–829 (2007).
Hunt, K.A. et al. Nat. Genet. 40, 395–402 (2008).
Zhernakova, A., van Diemen, C.C. & Wijmenga, C. Nat. Rev. Genet. 10, 43–55 (2009).
Raychaudhuri, S. et al. PLoS Genet. 5, e1000534 (2009).
Altshuler, D., Daly, M.J. & Lander, E.S. Science 322, 881–888 (2008).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Plenge, R. Unlocking the pathogenesis of celiac disease. Nat Genet 42, 281–282 (2010). https://doi.org/10.1038/ng0410-281
Issue Date:
DOI: https://doi.org/10.1038/ng0410-281
This article is cited by
-
Effect of wheat grain protein composition on end-use quality
Journal of Food Science and Technology (2020)
-
Leaky Gut and Autoimmune Diseases
Clinical Reviews in Allergy & Immunology (2012)