Access

Letter

Nature Genetics 41, 824–828 (1 July 2009) | doi:10.1038/ng.396

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20

Melanie Bahlo , David R Booth , Simon A Broadley , Matthew A Brown , Simon J Foote , Lyn R Griffiths , Trevor J Kilpatrick , Jeanette Lechner-Scott , Pablo Moscato , Victoria M Perreau , Justin P Rubio , Rodney J Scott , Jim Stankovich , Graeme J Stewart , Bruce V Taylor , James Wiley , Matthew A Brown , David R Booth , Glynnis Clarke , Mathew B Cox , Peter A Csurhes , Patrick Danoy , Karen Drysdale , Judith Field , Simon J Foote , Judith M Greer , Lyn R Griffiths , Preethi Guru , Johanna Hadler , Brendan J McMorran , Cathy J Jensen , Laura J Johnson , Ruth McCallum , Marilyn Merriman , Tony Merriman , Karen Pryce , Rodney J Scott , Graeme J Stewart , Lotfi Tajouri , Ella J Wilkins , Justin P Rubio , Melanie Bahlo , Matthew A Brown , Brian L Browning , Sharon R Browning , Devindri Perera , Justin P Rubio , Jim Stankovich , Simon Broadley , Helmut Butzkueven , William M Carroll , Caron Chapman , Allan G Kermode , Mark Marriott , Deborah Mason , Robert N Heard , Michael P Pender , Mark Slee , Niall Tubridy , Jeanette Lechner-Scott , Bruce V Taylor , Ernest Willoughby , Trevor J Kilpatrick , Melanie Bahlo , David R Booth , Simon A Broadley , Matthew A Brown , Simon J Foote , Lyn R Griffiths , Trevor J Kilpatrick , Jeanette Lechner-Scott , Pablo Moscato , Victoria M Perreau , Justin P Rubio , Rodney J Scott , Jim Stankovich , Graeme J Stewart , Bruce V Taylor , James Wiley , Melanie Bahlo , David R Booth , Simon A Broadley , Matthew A Brown , Simon J Foote , Lyn R Griffiths , Trevor J Kilpatrick , Jeanette Lechner-Scott , Pablo Moscato , Victoria M Perreau , Justin P Rubio , Rodney J Scott , Jim Stankovich , Graeme J Stewart , Bruce V Taylor , James Wiley , Matthew A Brown , David R Booth , Glynnis Clarke , Mathew B Cox , Peter A Csurhes , Patrick Danoy , Karen Drysdale , Judith Field , Simon J Foote , Judith M Greer , Lyn R Griffiths , Preethi Guru , Johanna Hadler , Brendan J McMorran , Cathy J Jensen , Laura J Johnson , Ruth McCallum , Marilyn Merriman , Tony Merriman , Karen Pryce , Rodney J Scott , Graeme J Stewart , Lotfi Tajouri , Ella J Wilkins , Justin P Rubio , Matthew A Brown , David R Booth , Glynnis Clarke , Mathew B Cox , Peter A Csurhes , Patrick Danoy , Karen Drysdale , Judith Field , Simon J Foote , Judith M Greer , Lyn R Griffiths , Preethi Guru , Johanna Hadler , Brendan J McMorran , Cathy J Jensen , Laura J Johnson , Ruth McCallum , Marilyn Merriman , Tony Merriman , Karen Pryce , Rodney J Scott , Graeme J Stewart , Lotfi Tajouri , Ella J Wilkins , Justin P Rubio , Melanie Bahlo , Matthew A Brown , Brian L Browning , Sharon R Browning , Devindri Perera , Justin P Rubio , Jim Stankovich , Melanie Bahlo , Matthew A Brown , Brian L Browning , Sharon R Browning , Devindri Perera , Justin P Rubio , Jim Stankovich , Simon Broadley , Helmut Butzkueven , William M Carroll , Caron Chapman , Allan G Kermode , Mark Marriott , Deborah Mason , Robert N Heard , Michael P Pender , Mark Slee , Niall Tubridy , Jeanette Lechner-Scott , Bruce V Taylor , Ernest Willoughby , Trevor J Kilpatrick , Simon Broadley , Helmut Butzkueven , William M Carroll , Caron Chapman , Allan G Kermode , Mark Marriott , Deborah Mason , Robert N Heard , Michael P Pender , Mark Slee , Niall Tubridy , Jeanette Lechner-Scott , Bruce V Taylor , Ernest Willoughby & Trevor J Kilpatrick

To identify multiple sclerosis (MS) susceptibility loci, we conducted a genome-wide association study (GWAS) in 1,618 cases and used shared data for 3,413 controls. We performed replication in an independent set of 2,256 cases and 2,310 controls, for a total of 3,874 cases and 5,723 controls.