Access

News and Views

Nature Genetics 41, 509–510 (1 May 2009) | doi:10.1038/ng0509-509

TMPRSS2-ERG and PTEN loss in prostate cancer

Jeremy A Squire

Recommendations over screening for early diagnosis of prostate cancer have recently gained attention, with increasing concern that the introduction of routine prostate-specific antigen (PSA) blood testing has led to significant overtreatment of prostate cancer. This debate highlights the need to better understand the primary molecular determinants that drive prostate cancer.