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Nature Genetics 41, 510 - 512 (2009)
doi:10.1038/ng0509-510

X-cess of variants in XLMR

David L Nelson1 & Richard A Gibbs1

  1. David L. Nelson and Richard A. Gibbs are at Baylor College of Medicine, Houston, Texas, USA.
    e-mail: nelson@bcm.tmc.edu or e-mail: agibbs@bcm.tmc.edu


A new study reports large-scale systematic resequencing of the coding exons of the X chromosome in males with X-linked mental retardation (XLMR), illustrating the challenge of sorting through large amounts of benign variation in order to identify disease-causing sequence changes.

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