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Nature Genetics 41, 7 - 8 (2009)
doi:10.1038/ng0109-7
Searching for targets of viral microRNAs
Denise Whitby1
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Denise Whitby is in the Viral Oncology Section, AIDS and Cancer Virus Program, SAIC-Frederick, National Cancer Institute at Frederick, PO Box B, Frederick, Maryland 21701, USA.
e-mail: whitbyd@ncifcrf.gov
Abstract
The identification of targets of virally encoded microRNAs is essential to understanding their role in the viral life cycle. A new study reports the successful use of a microarray-based approach to identify a key target of a microRNA encoded by Kaposi's sarcoma–associated herpesvirus, with implications for microRNA target identification in other contexts as well.
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RESEARCH
Tandem array?based expression screens identify host mRNA targets of virus-encoded microRNAsNature Genetics Letter (01 Jan 2009)
A viral microRNA functions as an orthologue of cellular miR-155Nature Letters to Editor (13 Dec 2007)
Human herpesvirus miRNAs statistically preferentially target host genes involved in cell signaling and adhesion/junction pathwaysCell Research Letter
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