News and Views
Nature Genetics 41, 10 - 11 (2009)
doi:10.1038/ng0109-10
Protein demethylation required for DNA methylation
Hans-Rudolf Hotz1 & Antoine H F M Peters1
- Antoine H.F.M. Peters and Hans-Rudolf Hotz are at the Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH-4058 Basel, Switzerland.
Correspondence to: Antoine H F M Peters1 e-mail: antoine.peters@fmi.ch
Abstract
DNA methylation is an epigenetic mark directing stable, heritable gene silencing through development. A new study uncovers the importance of demethylation of the DNA methyltransferase-1 for maintenance of DNA methylation.
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