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Mapping the strand-specific transcriptome of fission yeast

Pervasive genome-wide transcription is widespread in eukaryotic cells, but key features of the transcriptome have yet to be fully characterized. A new study using antibody-based detection of RNA-DNA duplexes on tiling arrays now reveals a complex, strand-specific transcriptional world in fission yeast.

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Figure 1: Three levels of resolution showing pervasive interleaved transcription.

References

  1. Birney, E. et al. Nature 447, 799–816 (2007).

    Article  CAS  PubMed  Google Scholar 

  2. Gingeras, T.R. Genome Res. 17, 682–690 (2007).

    Article  CAS  PubMed  Google Scholar 

  3. Kapranov, P. et al. Science 316, 1484–1488 (2007).

    Article  CAS  PubMed  Google Scholar 

  4. Dutrow, N. et al. Nat. Genet. 40, 977–986 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Efroni, S. et al. Cell Stem Cell 2, 437–447 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Katayama, S. et al. Science 309, 1564–1566 (2005).

    Article  PubMed  Google Scholar 

  7. Manak, J.R. et al. Nat. Genet. 38, 1151–1158 (2006).

    Article  CAS  PubMed  Google Scholar 

  8. Carninci, P. et al. Science 309, 1559–1563 (2005).

    Article  CAS  PubMed  Google Scholar 

Download references

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The author is a consultant and former employee of Affymetrix, Inc.

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Gingeras, T. Mapping the strand-specific transcriptome of fission yeast. Nat Genet 40, 935–936 (2008). https://doi.org/10.1038/ng0808-935

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