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Nature Genetics 40, 686 - 688 (2008)
doi:10.1038/ng0608-686

New susceptibility genes for ulcerative colitis

Patrick C Dubois1 & David A van Heel1

  1. Patrick C. Dubois and David A. van Heel are at the Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, 4 Newark Street, London E1 2AT, UK. e-mail: d.vanheel@qmul.ac.uk


Genome-wide association studies in Crohn's disease have convincingly identified multiple risk variants. Two new studies in ulcerative colitis, a related inflammatory bowel disease, now reveal a glimpse of the overlapping spectrum of risk variants, highlighting both the commonalities and the unique features of these disorders.

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