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Letter

Nature Genetics 40, 460–465 (1 April 2008) | doi:10.1038/ng.112

Newly identified prion linked to the chromatin-remodeling factor Swi1 in Saccharomyces cerevisiae

Zhiqiang Du , Kyung-Won Park , Haijing Yu , Qing Fan & Liming Li

SWI/SNF, an evolutionarily conserved ATP-dependent chromatin-remodeling complex, has an important role in transcriptional regulation. In Saccharomyces cerevisiae, SWI/SNF regulates the expression of |[sim]|6% of total genes through activation or repression.