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Nature Genetics 40, 1391–1392 (1 December 2008) | doi:10.1038/ng1208-1391

Cell cycle micromanagement in embryonic stem cells

V Narry Kim

Embryonic stem (ES) cells are derived from the inner cell mass of an early-stage embryo known as a blastocyst. ES cells can differentiate into all cell types of the adult body and, in the absence of stimuli, can infinitely divide without losing the capacity of self-renewal.