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Nature Genetics 40, 1272–1273 (1 November 2008) | doi:10.1038/ng1108-1272

Wilms tumor and constitutional epigenetic defects

Andrea Riccio

Constitutional defects affecting the imprinted gene cluster located at chromosome 11p15.5 cause a variety of syndromes characterized by congenital growth disorders, either growth enhancement or growth retardation.