News and Views
Nature Genetics 40, 1148 - 1149 (2008)
doi:10.1038/ng1008-1148
Casting an eye on the Krebs cycle
Arnold Munnich1
-
Arnold Munnich is at the Université Paris Descartes and Hôpital Necker-Enfants Malades, 75783, Paris 15, France.
e-mail: arnold.munnich@inserm.fr
Abstract
A new study identifies recessive, loss-of-function mutations in IDH3B, encoding a subunit of the NAD-specific isocitrate dehydrogenase, in individuals with retinitis pigmentosa. The lack of any obvious clinical signs in other tissues in these individuals forces a reassessment of the physiological role of this enzyme outside of the retina.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Mitochondria, from cell death to proliferationNature Genetics News and Views (01 Apr 2002)
Screening Correlation of genotype and phenotype in paragangliomaNature Reviews Endocrinology News and Views (01 Nov 2009)
RESEARCH
Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycleNature Genetics Letter (01 Oct 2008)
Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancerNature Genetics Letter (01 Apr 2002)
See all 5 matches for Research
