News and Views
Nature Genetics 40, 10 - 11 (2008)
doi:10.1038/ng0108-10
Basal bodies, kinocilia and planar cell polarity
Jeffrey D Axelrod1
- Jeffrey D. Axelrod is in the Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA. e-mail: jaxelrod@stanford.edu
Abstract
Primary cilia and planar cell polarity (PCP) proteins both contribute to cell polarization, but their relationship is unclear. A new study shows that, in the organ of Corti, primary cilia are required for morphological polarization of sensory hair cells and function downstream of the PCP signaling proteins.
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