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Nature Genetics 39, 1053 - 1054 (2007)
doi:10.1038/ng0907-1053
IL-7R
and multiple sclerosis risk
John B Harley1
- John B. Harley is in the Arthritis and Immunology Program at the Oklahoma Medical Research Foundation, 825 N.E. 13th Street, Oklahoma City, Oklahoma 73104, USA, and the US Department of Veterans Affairs Medical Center, Oklahoma City, Oklahoma 73104, USA. e-mail: harley@omrf.org
Abstract
The discovery of genetic risk factors for multiple sclerosis has proven difficult. IL-7R
, encoded by IL7R, is a pleiomorphic cytokine receptor now implicated in the pathogenesis of multiple sclerosis in independently replicated genetic association studies.
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