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Nature Genetics 39, 938 - 939 (2007)
doi:10.1038/ng0807-938
A step forward for restless legs syndrome
Emmanuel Mignot1
- Emmanuel Mignot is at the Center for Narcolepsy, Stanford University, Palo Alto, California 94304, USA. e-mail: mignot@stanford.edu
Abstract
Two genome-wide association studies report three loci predisposing to restless legs syndrome, a common sleep disorder also associated with periodic limb movements during sleep. The identified variants account for a large portion of population-attributable risk in individuals of European ancestry and may preferentially affect various symptoms of the disorder.
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