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Procedures for microattribution need to be established by journals and databases so that data producers have an overwhelming incentive to deposit their results in public databases and thereby to receive quantitative credit for the use of every published data accession.
A 23-nucleotide sequence conserved in species from rice to Arabidopsis thaliana in a family of noncoding RNAs resembles a cleavable miRNA target site—but not exactly. A new study demonstrates that the site is not cleaved and instead negatively regulates miRNA activity through mimicry.
Several devastating genetic diseases illustrate that peroxisomes are essential to the development and functioning of the central nervous system. New work using a mouse model now shows that peroxisome integrity in oligodendrocytes is essential for axonal maintenance.
Two genome-wide association studies report three loci predisposing to restless legs syndrome, a common sleep disorder also associated with periodic limb movements during sleep. The identified variants account for a large portion of population-attributable risk in individuals of European ancestry and may preferentially affect various symptoms of the disorder.