News and Views
Nature Genetics 39, 817 - 818 (2007)
doi:10.1038/ng0707-817
ENCODE and our very busy genome
Steven Henikoff1
- Steven Henikoff is at the Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. North, Seattle, Washington 98109, USA. e-mail: steveh@fhcrc.org
Abstract
The much-anticipated publication of the ENCODE pilot project, representing a detailed and comprehensive characterization of 1% of the human genome, has demonstrated how little we truly understand about how our genes are regulated. Transcripts are nearly everywhere, regulatory sequences remain poorly defined and evolutionary conservation is a surprisingly inadequate predictor of transcriptional features.
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RESEARCH
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectNature Article (14 Jun 2007)
