News and Views


Nature Genetics 39, 579 - 580 (2007)
doi:10.1038/ng0507-579

Multiple prostate cancer risk variants on 8q24

John S Witte1

  1. John S. Witte is in the Department of Epidemiology and Biostatistics and the Institute for Human Genetics, University of California, San Francisco, San Francisco, California 94143-0794, USA. e-mail: jwitte@ucsf.edu


Three new reports leverage genome-wide studies to localize and replicate multiple independent variants strongly associated with prostate cancer on chromosome 8q24. These findings provide a significant advance toward deciphering the genetic basis of this disease, although further work is needed to clarify the biological mechanisms underlying these associations.

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