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Nature Genetics 39, 293 (1 March 2007) | doi:10.1038/ng0307-293
Research highlights
Abstract
Infectious retrovirus and prostate cancer The R462Q variant of the endoribonuclease RNase L has been reported to be associated with familial prostate cancer, albeit with mixed support in follow-up studies. As RNase L functions in the interferon antiviral response, it had been proposed that a virus might be associated with some cases of prostate cancer, and a recent study identified a gammaretrovirus in prostate tumors from men carrying the R462Q variant.
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