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Letter
Nature Genetics 39, 1483–1487 (1 December 2007) | doi:10.1038/ng.2007.24
Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia
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Abstract
Hypertriglyceridemia is a hallmark of many disorders, including metabolic syndrome, diabetes, atherosclerosis and obesity. A well-known cause is the deficiency of lipoprotein lipase (LPL), a key enzyme in plasma triglyceride hydrolysis.
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